Gene Expression
EuReGene's primary Gene Expression Database contains in situ gene expression patterns in the developing and adult mouse kidney and will, in future, house microarray data for a number of species. Annotation of in situ expression patterns is ongoing. The database interface allows for browsing per gene, with relevant links to external databases, per anatomical component of the developing and adult mouse kidney or per experiment for both microarray and in situ data.
Anatomy
Histological sections of mouse kidney at Theiler Stage 26 (TS26) of development have been photographed and digitally reconstructed. Anatomical components of the nephron have been identified and painted onto the reconstruced images. Nephron components from different painted sections can be selected, allowing gene expression patterns in the selected components to be identified.
Mutant Phenotype
Mouse mutant phenotype data has been collected from several EuReGene partners. The genes contributing to each of the mutant phenotypes will ultimately link to further data (including gene expression data) on the relevant gene. Anatomical components affected by a particular phenotype will permit gene expression-based queries to determine other genes which may also be expressed in the particular component.
